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Rainer K Brachmann Selected Research

vesencumab

8/2014A phase I study of the human monoclonal anti-NRP1 antibody MNRP1685A in patients with advanced solid tumors.
5/2014A Phase Ib study evaluating MNRP1685A, a fully human anti-NRP1 monoclonal antibody, in combination with bevacizumab and paclitaxel in patients with advanced solid tumors.
9/2012Anti-neuropilin-1 (MNRP1685A): unexpected pharmacokinetic differences across species, from preclinical models to humans.

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Rainer K Brachmann Research Topics

Disease

13Neoplasms (Cancer)
10/2020 - 04/2004
2Nausea
10/2020 - 05/2014
2Exanthema (Rash)
10/2020 - 08/2014
2Fatigue
12/2017 - 05/2014
1Breast Neoplasms (Breast Cancer)
11/2020
1Vomiting
10/2020
1Adenocarcinoma
10/2020
1Pancreatic Neoplasms (Pancreatic Cancer)
10/2020
1Dysgeusia (Parageusia)
12/2017
1Spasm (Spasms)
12/2017
1Pruritus (Itching)
08/2014
1Proteinuria
05/2014
1Neutropenia
05/2014
1Dysphonia (Spastic Dysphonia)
05/2014
1Alopecia (Baldness)
05/2014
1Thrombocytopenia (Thrombopenia)
05/2014
1Lung Neoplasms (Lung Cancer)
12/2012
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
12/2012

Drug/Important Bio-Agent (IBA)

4Proteins (Proteins, Gene)FDA Link
07/2007 - 04/2004
3vesencumabIBA
08/2014 - 09/2012
3Pharmaceutical PreparationsIBA
05/2014 - 08/2004
3Tumor Suppressor Protein p53IBA
02/2007 - 04/2004
2Paclitaxel (Taxol)FDA LinkGeneric
11/2020 - 05/2014
2Monoclonal AntibodiesIBA
05/2014 - 09/2012
1GemcitabineFDA Link
10/2020
1Recombinant Fusion ProteinsIBA
10/2020
1130-nm albumin-bound paclitaxelIBA
10/2020
1Aspartate Aminotransferases (Aspartate Transaminase)IBA
10/2020
1Dihydrotachysterol (AT 10)IBA
12/2017
1LigandsIBA
12/2017
1Dexamethasone (Maxidex)FDA LinkGeneric
08/2014
1Bevacizumab (Avastin)FDA Link
05/2014
1Phosphatidylinositols (Phosphatidylinositol)IBA
12/2012
1Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
12/2012
1Biomarkers (Surrogate Marker)IBA
12/2012
1Neuropilin-1IBA
09/2012
1Amino AcidsFDA Link
02/2007
13-hydroxyphenyltrimethylammoniumIBA
03/2006
1prothymosin alphaIBA
03/2006
1Oncogene Proteins (Oncogene Protein)IBA
03/2006
1Adenosine Triphosphate (ATP)IBA
07/2004
1Transcription Factors (Transcription Factor)IBA
04/2004

Therapy/Procedure

2Therapeutics
02/2007 - 04/2004
1Premedication
08/2014